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Describe

pkc beta Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways..

xocdia88 vip In vivo, PKC-beta-1 colocalized with AR and LSD1 on target gene promoters and phosphorylated H3T6 after androgen-induced gene expression. RNAi-mediated knockdown of PKC-beta-1 abrogated H3T6 phosphorylation, enhanced demethylation at H3K4, and inhibited AR-dependent transcription.

xs247.xổ số vip Study the PKC pathway's role in cellular signaling and regulation. Explore the molecular mechanisms & signaling events governed by this pathway. Click.